| ncRNA name | SetD7 siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Bos taurus |
| Tissues/Cell_line | bovine retinal endothelial cells (BRECs) |
| Methods | siRNA transfection, Chromatin immunoprecipitation (CHIP), qPCR, Western blot |
| Expression pattern | associated |
| Functional description | SetD7-siRNA prevented increase in Sp1 binding at Keap1 promoter and Keap1 expression, and ameliorated decrease in Nrf2-regulated antioxidant genes. |
| PubMed ID | 25301875 |
| Year | 2014 |
| Title | Epigenetic modifications of Keap1 regulate its interaction with the protective factor Nrf2 in the development of diabetic retinopathy. |
| Drug-related ncRNA | NO |
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